First of a two-part special. Ten volunteers have come together for an extraordinary test. Five are ‘normal’ and the other five have been officially diagnosed as mentally ill. Horizon asks if you can tell who is who, and considers where the line between sanity and madness lies.
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National Institutes of Health-funded researchers discovered that people with disorders traditionally thought to be distinct — autism, ADHD, bipolar disorder, major depression and schizophrenia — were more likely to have suspect genetic variation at the same four chromosomal sites. These included risk versions of two genes that regulate the flow of calcium into cells. Bruce Cuthbert, Ph.D., director of NIMH’s Division of Adult Translational Research, explains the significance of the study findings for diagnosis and treatment of mental illnesses.
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